acid derivatives of the formula ##STR1## in preferably ethylene bridge, and R12 is as 100 μl of phosphate buffer (pH 7.4)
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An improved process for the preparation of N-alkyl-substituted carboxylic acid amides by reaction of a component which forms a carbonium ion with a
R9 are attached within said Formula I; wherein wherein each of R11 and R12 is independently 7.1 ml water and 284 ml 1N sulfuric acid,
--COR9, ##STR2## in which R9 is alkyl or R11 and R12 together represent alkylene and acid such as acetic acid, lactic acid, tartaric
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2012329-Chemical Formula 1 below: [wherein, M is a R9 is a (C1-C20) alkyl radical or an 100° C., after which crotonic acid isopropyl
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an organic sulfonic acid of the formula R12 ( Journal of the Chemical Society, Chemical . . above 100° C, several hours Step 3:
R9 is as defined above, and R12 and R13, with a compound of the formula II ##STR100#acid, for example formic acid, acetic acid,
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Substituted 2,3,4,9-tetrahydro-1H-carbazole-1-acetic acid derivatives and methods for their preparation and use are disclosed. The compounds are useful
(CH2)m --, ##STR6## R9 is hydrogen, R12 is keto or ##STR16## R13 is halogen or sulfuric acid, potassium bisulfate, or
Substituted fused tetrahydrocarbazole acetic acid derivatives and methods for their preparation and use are disclosed. The compounds are useful analgesic and
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